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Analyses of associations between haplotypes of MLH1 and PFS/OS.
| PFS | OS | ||||||
|---|---|---|---|---|---|---|---|
| Haplotypes | Haplotype frequencies (%) | HR | 95% CI | P-value | HR | 95% CI | P-value |
| AGa | 51.00 | ||||||
| GAa | 6.73 | 1.84 | 1.07–3.16 | 0.027 | 1.50 | 0.75–3.00 | 0.253 |
| GGa | 42.31 | 0.95 | 0.70–1.27 | 0.712 | 0.87 | 0.58–1.30 | 0.490 |
Haplotype was composed in the order of rs1800734 then rs9852810; AG was the most common haplotype. PFS, progression-free survival; OS, overall survival; CI, confidence interval; HR, hazard ratio; MLH1, MutL homolog 1.
