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. 2017 Nov 13;15(1):917–925. doi: 10.3892/ol.2017.7396

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Copyright: © Yu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — The incidence of C-KIT mutations is positively correlated with APP expression. (A) APP relative expression level was evaluated by reverse transcription-quantitative polymerase chain reaction. The dashed line represents the cut-off value (0.12440) of high and low APP expression level. APP levels were significantly higher in the APP-H group (with relative levels of APP ≥0.12440) than in the APP-L group (with relative levels of APP <0.12440). (B) Significantly increased APP expression levels were observed in C-KIT-mutated patients. APP-H, APP-high expression; APP-L, APP-low expression; APP, amyloid precursor protein.