Table III.
Fluorescent signal strength of the analyzed signaling proteins in relation to the expression of the PTEN protein.
| PTEN expression | ||
|---|---|---|
| Marker | Negative (n=26) | Positive (n=24) |
| PTEN (pan) | Mean=156.29 (49–250)a | |
| MarkerMedian=167 | ||
| SD=57.1 | ||
| Mean=108.08 (49–167) | Mean=206.5 (173–250) | |
| Median=105 | Median=211.5 | |
| SD=33.58 | SD=21.68 | |
| phospho-AKT (Thr308) | Mean=75.92 (28–153) | Mean=49.04 (18–117) |
| SD=27.98 | SD=29.16 | |
| phospho-PDK1 (Ser241) | Mean=74.16 (43–107) | Mean=61.00 (34–101) |
| SD=16.47 | SD=18.25 | |
a
range; SD, standard deviation; P-value, level of statistical significance; AKT, AKT serine/threonine kinase; PDK-1, 3-Phosphoinositide-dependent kinase 1; PTEN, phosphatase and tensin homolog deleted on chromosome 10; SD, standard deviation.