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AZ-BPS targeting to CAIX in patient-derived tissue samples. Correlation between CAIX expression as inferred from studies with human anti-CAIX antibody (green) and the fluorescent intensity of AZ-BPS (red) seen in cryosectioned tumor tissues obtained from a human breast cancer patient. A strong degree of colocalization was seen as inferred from the Pearson’s coefficient value (0.84) (yellow color area, randomly selected n = 5 area).
