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Genistein suppresses Skp2 expression. (A) The expression of Skp2 and its downstream targets, p21 and p27, was detected by western blot analysis in genistein-treated MDA-MB-231 cells (left panel) and SKBR3 cells (right panel). (B) Quantitative expression levels determined by densitometric evaluation of the immunoblot images. *P<0.05 vs. control group. Skp2, S-phase kinase-associated protein 2.
