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. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Osteoporos Int. 2017 Oct 23;29(1):69–77. doi: 10.1007/s00198-017-4261-3

Table 4.

The Association Between Protein Intake (by Source) and Bone Strength Parameters from High Resolution Peripheral Quantitative Computed Tomography (HR-pQCT) of the Diaphyseal Tibia.

Diaphyseal Tibia Base Model Multivariate model
Dairy protein Non-dairy animal protein Plant protein Dairy protein Non-dairy animal protein Plant protein
Failure load 0.10 (0.00, 0.20) 0.00 (−0.07, 0.07) −0.06 (−0.17, 0.06) 0.09 (−0.01, 0.18) 0.00 (−0.07, 0.06) −0.03 (−0.15, 0.08)
BMD 0.18 (0.07, 0.28) 0.01 (−0.06, 0.08) 0.10 (−0.01, 0.22) 0.18 (0.08, 0.29) 0.00 (−0.07, 0.07) 0.11 (−0.01, 0.22)
Total area −0.05 (−0.15, 0.06) −0.01 (−0.08, 0.06) −0.11 (−0.23, 0.01) −0.07 (−0.17, 0.03) −0.01 (−0.08, 0.06) −0.09 (−0.20, 0.03)
Cortical BMD 0.06 (−0.04, 0.16) −0.03 (−0.10, 0.04) 0.17 (0.06, 0.29) 0.06 (−0.04, 0.17) −0.04 (−0.11, 0.03) 0.15 (0.04, 0.27)
Cortical area 0.10 (−0.00, 0.20) 0.01 (−0.06, 0.08) −0.06 (−0.18, 0.05) 0.08 (−0.01, 0.18) 0.01 (−0.06, 0.07) −0.03 (−0.15, 0.08)
Cortical thickness 0.16 (0.06, 0.26) 0.00 (−0.07, 0.07) 0.02 (−0.12, 0.11) 0.16 (0.05, 0.26) 0.00 (−0.07, 0.07) 0.01 (−0.10, 0.13)
Cortical porosity −0.01 (−0.11, 0.10) 0.00 (−0.07, 0.07) −0.04 (−0.16, 0.08) −0.01 (−0.12, 0.09) 0.01 (−0.06, 0.08) −0.02 (−0.14, 0.10)
*

Effect size (beta coefficient with unit=SD). Protein measured as percentage of total energy intake (TEI), SD=2.9% TEI.

Base model adjusted for age, clinical center, total calories.

Multivariate model adjusted for age, clinical center, total calories, limb length, education, race/ethnicity, marital status, smoking, alcohol intake, physical activity level, corticosteroid use, supplement use (calcium and vitamin D), and osteoporosis medications.