Fig. 2.
A significant correlation was detected between Aβ plaque burden and total number of NFTs per 10 μm-thick section (R2=0.15, p=0.0015) (a). [F-18]-AV-1451 autoradiography signal significantly correlated with total number of NFTs per 10 μm-thick section (R2=0.71, p<0.0001) (b), and Aβ plaque load (R2=0.26, p<0.0001) (c). Abbreviations: Aβ = β-amyloid; EC = entorhinal cortex; IHC = immunohistochemistry; NFT = neurofibrillary tangles; STS = superior temporal sulcus; VC = visual cortex; PHF = paired helical filament