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. Author manuscript; available in PMC: 2018 Oct 1.
Published in final edited form as: Int J Parasitol. 2017 Sep 9;47(12):753–763. doi: 10.1016/j.ijpara.2017.08.006

Fig. 1.

Fig. 1

Predicted and observed bumpked kinase inhibitor efficacy against Cryptosporidium parvum in adult female IFN-γ knockout mice. (A) Gastroplus predicted values for titrated oral (PO) doses of BKI 1369 given once daily (QD) on days 6–10 p.i. (B) Observed in vivo efficacy of titrated PO doses of BKI 1369 given QD on days 6–10 p.i.