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Microsomal stability and plasma protein binding of bumped kinase inhibitor 1369.
| Species | Microsomal stability Time (min) |
Plasma protein binding (% bound) |
|---|---|---|
| Human | >120 | 77 |
| Mouse | >120 | 37 |
| Rat | >120 | 76 |
| Cattle | >120 | 93 |
| Dog | >120 | 40 |
| Cat | >120 | ND |
| Monkey | >120 | ND |
ND, not determined.
