Table 2.

Associations between leptin and BMD in various regions

	Univariable		Multivariablea
	β(95% CI)	p value	β(95% CI)	p value
Total body BMD	−0.011(− 0.026,0.004)	0.155	− 0.019(− 0.034,-0.005)	0.009
Spine BMD	0.004(− 0.013,0.021)	0.653	− 0.010(− 0.028,0.007)	0.248
Hip BMD	− 0.010(− 0.025,0.006)	0.213	− 0.018(− 0.034,-0.003)	0.018
Total femur BMD	− 0.007(− 0.023,0.008)	0.352	− 0.018(− 0.034,-0.002)	0.024
Femoral neck	−0.010(− 0.025,0.006)	0.218	−0.016(− 0.032,0.000)	0.048
Wards triangle	−0.007(− 0.025,0.011)	0.462	−0.012(− 0.029,0.006)	0.194
Greater trochanter	−0.004(− 0.018,0.009)	0.538	−0.013(− 0.026,0.001)	0.074
Femoral shaft	−0.008(− 0.028,0.011)	0.386	−0.026(− 0.046,-0.006)	0.012

Dependent variable: BMD in respective compartment

Independent variable: leptin

Data in bold denote statistically significant results

BMD bone mineral density, BMI body mass index, ROA radiographic osteoarthritis

^aAdjusted for age, sex, BMI and ROA