Table 5.
Frequency of selected protocol features among “successful” or “modestly successful” (for accrual of AA and/or HA; n=8) versus “unsuccessful” (for accrual of both AA and HA; n=3) with regard to accrual diversity
| Feature | Proportion (%) of protocols with selected feature that were “successful” or “modestly successful” |
Proportion (%) of protocols with selected feature that were “unsuccessful” |
|
|---|---|---|---|
| Protocol Design | Randomized n=4 | 3/4 (75%) | 1/4 (25%) |
| Not Randomized n=6 | 5/6 (83%) | 1/6 (17%) | |
| Protocol Eligibility | Early stage disease n=8 | 6/8 (75%) | 2/8 (25%) |
| Regional or locally advanced disease n=2 | 2/2 (100%) | 0/2 (0%) | |
| Protocol Features | Investigational systemic therapy plus surgery n=3 | 3/3 (100%) | 0/3 (0%) |
| Primary surgical study n=7 | 5/7 (71%) | 2/7 (29%) | |