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. 2018 Jan 18;14(1):e1007135. doi: 10.1371/journal.pgen.1007135

Table 2. Known histological associations for single genes within signatures.

Signature Gene(s) Ref
Squamous Bmp2, Bmp4, Bmp7 [66, 67]
Squamous Krt1, Krt10, Krt14, Krt16, K17 [6871]
Squamous Wnt6 [72]
Squamous Sprr1b [73]
EMT Up Vegfc [74]
EMT Up Zeb1 [75]
EMT Up Vim [75]
EMT Down Epcam [76]
EMT Down Cldn1, Cldn3 [77, 78]
EMT Down Cdh1 [75, 79]
Papillary Krt19 [80]
Papillary Hey2 [81]
Papillary Muc 15 [82]
Adenomyoepithelial Tnni2 [83]