Table 2. Known histological associations for single genes within signatures.
Signature | Gene(s) | Ref |
---|---|---|
Squamous | Bmp2, Bmp4, Bmp7 | [66, 67] |
Squamous | Krt1, Krt10, Krt14, Krt16, K17 | [68–71] |
Squamous | Wnt6 | [72] |
Squamous | Sprr1b | [73] |
EMT Up | Vegfc | [74] |
EMT Up | Zeb1 | [75] |
EMT Up | Vim | [75] |
EMT Down | Epcam | [76] |
EMT Down | Cldn1, Cldn3 | [77, 78] |
EMT Down | Cdh1 | [75, 79] |
Papillary | Krt19 | [80] |
Papillary | Hey2 | [81] |
Papillary | Muc 15 | [82] |
Adenomyoepithelial | Tnni2 | [83] |