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. Author manuscript; available in PMC: 2018 Jan 18.
Published in final edited form as: Sci Transl Med. 2017 Aug 16;9(403):eaal2717. doi: 10.1126/scitranslmed.aal2717

Fig. 2. Pathways differentially regulated in patients with early Lyme disease and STARI.

Fig. 2

The 122 presumptively identified MFs were analyzed using MetaboAnalyst to identify perturbed pathways between early Lyme disease and STARI. The color and size of each circle is based on P values and pathway impact values. Pathways with a > 0.1 impact were considered to be perturbed and differentially regulated between patients with early Lyme disease and STARI. A total of four pathways were affected: 1) glycerophospholipid metabolism; 2) sphingolipid metabolism; 3) valine, leucine and isoleucine biosynthesis; and 4) phenylalanine metabolism.