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. Author manuscript; available in PMC: 2018 Dec 1.
Published in final edited form as: Crit Rev Oncol Hematol. 2017 Sep 8;120:217–226. doi: 10.1016/j.critrevonc.2017.09.003

Figure 4.

Figure 4

Algorithm of using bisphosphonates as an adjuvant therapy. BP: bisphosphonate. Always use Include Vitamin D 1000–2000 international units and calcium 1000 mg/day and ensure vitamin D level is adequate (> 30 ng/ml) while initiating bisphosphonate. If vitamin D level is not in normal range, it must be corrected with higher doses of vitamin D to increase the level to > 30 ng/ml. Adapted from (48) with permission.