Table 2.
Hemodynamic changes
| MAP (mmHg) | P value | HR (b/min) | P value | |||||
|---|---|---|---|---|---|---|---|---|
| GroupD0 (n = 25) |
Group D1 (n = 26) |
Group D2 (n = 24) |
Group D0 (n = 25) |
Group D1 (n = 26) |
Group D2 (n = 24) |
|||
| Baseline | 81 ± 7 | 80 ± 6 | 79 ± 6 | 0.728 | 108 ± 13 | 109 ± 12 | 107 ± 12 | 0.924 |
| Just after pre-medicine | 81 ± 7 | 72 ± 8*^ | 72 ± 6* ^ | <0.000 | 109 ± 13 | 94 ± 10*^ | 92 ± 9*^ | <0.000 |
| Just before extubation | 78 ± 7 | 74 ± 8*^ | 73 ± 7*^ | <0.02 | 105 ± 10 | 99 ± 10*^ | 96 ± 9*^ | <0.009 |
| One min after extubation | 84 ± 5# | 76 ± 7^ | 76 ± 7^ | <0.002 | 115 ± 13# | 104 ± 9^ | 102 ± 9^ | <0.006 |
| Five min after extubation | 82 ± 7# | 76 ± 7^ | 76 ± 7^ | <0.029 | 115 ± 13# | 104 ± 10^ | 101 ± 10^ | <0.008 |
Data are expressed as mean ± standard deviation (SD) (One-way ANOVA test)
MAP = arterial blood pressure, HR = heart rate
Group D0 = saline group, Group D1 = dexmedetomidine group (1 μg·kg−1), Group D2 = dexmedetomidine group (2 μg·kg−1)
*P < 0.05 compared with values of baseline, #P < 0.05 compared with values just before extubation, ^ P < 0.05 compared with Group D0