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Evolution of the mean of individual phenotypes without considering the signaling pathway, and setting ᾱP to different values. Although the general behavior is quite similar, some differences in the growth dynamics are visible. Higher ᾱP values lead to faster and greater growth of proliferative cells. As the availability of oxygen is limited, a greater number of proliferative cells cause a faster consumption of the oxygen supply, leading to faster stagnation of tumor growth.
