Fig. 7.

Fullerenol NPs interact with gut microbiota during in vitro gut flora fermentation. a Fullerenols concentration changes in the fermentation solution; b effects of the final concentrations of different fullerenols after in vitro fermentation; c-e responses of Bifidobacterium, Clostridium IV, and Allbaculum spp. to inulin and fullerenol NPs; ^*P < 0.05, ^**P < 0.01, ^***P < 0.001 vs NC. f PET images of ⁶⁴Cu- C₆₀ at 0.5, 1, 2, and 6 h after single oral administration. g Excretion curves of ⁶⁴Cu-C₆₀ at 1, 2, 4, 6, and 24 h after single oral administration. All data points represent three animals per group. The total excretion was the sum of percentages of ⁶⁴Cu in all the waste (∑_0-turine + ∑_0-t feces) during 0-t not at the time point