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. 2018 Jan 17;9:11. doi: 10.1186/s13287-017-0753-5

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Heat map showing the cytokine concentrations secreted by MSCs cultured in two-dimensions (2D) and three dimensions (3D) after priming with IL-1α or IL-1β. Cytokines were analysed from the conditioned media of MSCs cultured in 2D and 3D, under untreated or primed conditions (IL-1α or IL-1β). Colours are assigned according to the relative scale of expression, ranging from 0 to 10, and representing fold-increase change versus the untreated condition