Table 3. Uni-variate analysis of factors associated with significant fibrosis (TE ≥ 7.1 kPa) according to logistic regression forward step-wise likelihood quotient in the whole cohort (n = 333).

Variable	Unadjusted OR (95% CI)	p-value
HCV positive	5.7 (3.4–9.7)	<0.001
ddI	3.3 (1.7–6.5)	<0.001
AZT	2.1 (1.2–3.4)	0.012
more than two different cART-regimes	1.9 (1.1–3.1)	0.004
Smoking	2.1 (1.2–3.6)
Fatty liver diagnosis in ultrasound	1.8 (1.1–2.9)	0.04
HIV<40c/ml	0.5 (0.3–0.9)	<0.001

TE = transient elastography; kPa = kilopascal; OR = odds ratio; CI = confidence interval; HCV = hepatitis C virus; ddI = didanosine; AZT = azidothymidine; HIV = human immunodeficiency virus; HBV = hepatitis B virus; c/ml: copies/milliliter