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. 2018 Jan 18;13(1):e0191099. doi: 10.1371/journal.pone.0191099

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© 2018 Egashira et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 6 — (A) Bone formation at 2 weeks post-transplantation. Scale bars represent 200 μm. The newly formed bone was integrated with the host bone. rhBMP-2 at 0.5 μg induced a limited amount of new bone formation while 1 μg rhBMP-2 and BMC (BMC represents the BMC group) promoted bone formation to surround β-TCP particles and connect to the host bone. Black asterisk: β-TCP particles, blue arrow: newly formed bone, and yellow dotted line: boundary between the host bone and specimen. (B) Comparison of the area (%) of newly formed bone in each group. PRP represents the PRP group. Values are the means ± standard deviations of five sections from each of the five specimens per group. The asterisk represents statistical significance (*p <0.05) among groups.