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. 2018 Jan 18;13(1):e0190935. doi: 10.1371/journal.pone.0190935

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© 2018 Martin et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 7 — A-C. Female. Aged female left ventricles had significant macrophage accumulation (B. 21.47±0.86 macrophages/hpf) compared to young controls (A. 15.57±0.96) and RLX reversed this aged-dependent macrophage accumulation (C. 11.72±1.26). D-F. Male. Male left ventricles showed no change in macrophage accumulation in aging (E. 2.13±0.51) or with RLX treatment (4.88±0.84) compared to young (0.65±0.27) male rats, and had less macrophages than females in each group. G. Quantification of macrophage accumulation. Blue: DAPI; Green: F4/80 macrophage marker; HPF: high power field. Data is reported as mean ± SEM. N.S.: Not significant. 60x magnification. Scale bar: 50 μm.