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| Upstream analysis of regulators | ||||
|---|---|---|---|---|
| Female | Male | |||
| Upstream regulator | Aging | RLX | Aging | RLX |
| Hydrogen Peroxide | Inhibited | Inhibited | ||
| NFkB (complex) | Activated | Inhibited | Inhibited | |
| TLR4 | Activated | Inhibited | ||
| IFNG | Activated | Inhibited | Inhibited | |
| IL6 | Activated | Inhibited | Inhibited | |
| LPS | Activated | Inhibited | Inhibited | |
| Sirolimus | Inhibited | Activated | ||
| TGFβ1 | Activated | Inhibited | Inhibited | |
| SMAD7 | Inhibited | Activated | Activated | |
