Table 2.

Regression coefficients showing effects of age and region on diffusion parameter changes

		Age2		Age		Region		Age × region
		Coefficient	p value	Coefficient	p value	Coefficient	p value	Coefficient	p value
GM	FA	0.594	<0.001	−13.163	<0.001	−20.076	0.013	0.926	0.304
	MD	—	—	−4.603	0.001	−37.863	0.028	−3.533	0.068
	AD	—	—	−12.055	<0.001	−94.541	<0.001	−1.729	0.417
	RD	—	—	−1.333	0.388	−16.440	0.379	−4.457	0.035
WM	FA	—	—	3.096	<0.001	24.853	<0.001	−1.481	0.036
	MD	−0.976	0.006	−10.189	0.081	−189.456	<0.001	7.976	0.001
	AD	−0.781	0.044	−11.068	0.092	−164.175	<0.001	5.683	0.033
	RD	−1.060	0.003	−9.959	0.088	−202.240	<0.001	9.130	<0.001

Bold values indicate significant effects of region and age × region interactions. Coefficient values are multiplied by 10³.