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. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Brain Struct Funct. 2017 Jul 27;223(1):195–210. doi: 10.1007/s00429-017-1482-3

Figure 2. Binge alcohol decreased cell proliferation and increased cell death in the dentate gyrus.

Figure 2

Cell proliferation was significantly decreased by binge alcohol in both sexes (A; arrowheads in panel a indicate Ki67+ cells). Cell death (B) was increased by binge alcohol in the dentate gyrus of both sexes (FJB+ cells indicated in panel b by arrowheads). Cell death in the dentate gyrus did not appear to be apoptotic in nature, as we found virtually no TUNEL+ cells in binged animals (C; left panel shows positive control with arrowhead pointing to TUNEL+ cell).