FIG. 3.
Six-pool (amide, intermediate exchanging amine, fast exchanging amine, rNOE, semi-solid MT, and water) model simulated Z-spectra (Slab) and corresponding EMR fitted reference spectra (Sref) (a, c) using values in bold in Table 1, and experimental Z-spectra (Slab) and corresponding EMR fitted reference spectra (Sref) on five healthy rat brains (b, d) with ω1 of 1 μT (a, b) and 3.6 μT (c, d), respectively. Two-pool (water and semi-solid component) model simulated reference spectra were also shown in (a, c) for comparison with Sref spectra. Note that Sref spectra are covered by the simulated reference spectra, indicating the success of the fitting approach. Error bars in (b, d) represent the standard deviations across subjects.