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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: Dev Neurobiol. 2017 Sep 14;78(2):152–162. doi: 10.1002/dneu.22533

Figure 4. Time kinetics of behavioral assessments on mice undergoing chronic variable stress (CVS).

Figure 4

Mice were exposed to 7 days (A), 14 days (B), or 21 days (C) of stress followed by behavioral assessments on each group. Only mice exposed to 7 days of stress displayed minor depressive-like behavior in splash test and novelty suppressed feeding (NSF) test, but not in forced swim test (FST). Mice exposed to 14 days or 21 days of stress displayed a stress habituation phenotype. For splash test and FST, * p<0.05, ** p<0.01 by two-tailed unpaired t-test. For NSF test, statistical significance was determined by two-tailed unpaired t-test corrected for multiple comparisons using Holm-Sidak method. * p<0.05, n=10–12 mice per group. Data represented as mean ± S.E.M.