Table 2.

Differential anatomical correlates of affect sharing and prosocial motivation.

Anatomic region and structure			Right Lateralized				Left Lateralized
Specific to Affect Sharing (AS)	Evident in both (AS+PM)	Specific to Prosocial Motivation (PM)	x	y	z	MaxT	x	y	z	MaxT
*Subcortical/striatal*
		Caudate	10	13	−3	4.68	−6	10	1	4.43
Amygdala			21	−10	−12	6.47^*	−25	−2	−18	4.53
Hippocampus			28	−8	−19	6.17^*	−12	−37	1	4.71
Pallidum			24	−8	−7	5.88^*				NS
	Putamen (AS)		30	−10	−10	5.29^*				NS
	Putamen (PM)		30	−8	−3	4.51^*				NS
Thalamus Proper			25	−29	−3	4.70^*	−13	−35	0	4.82
		Nucleus accumbens	9	15	−4	4.6				NS
*Temporal*
Temporal pole			21	10	−34	6.19^*	−27	9	−28	4.6
Entorhinal area			28	1	−18	5.98^*	−27	3	−21	4.94
Inferior temporal gyrus			27	3	−40	5.77^*				NS
Fusiform gyrus			39	−23	−21	5.72^*	−27	−31	−24	4.46
Middle temporal gyrus			57	6	−22	5.64^*				NS
Planum polare			42	−10	−9	5.48^*				NS
Posterior insula			40	−10	−7	5.36^*				NS
Parahippocampal gyrus			27	−31	−19	5.33^*	−15	−35	−1	4.75
Superior temporal gyrus			52	4	−21	5.12				NS
	Anterior insula (AS)		30	7	−16	5.00^*				NS
	Anterior insula (PM)		30	19	−13	5.08				NS
*Parietal*
Posterior cingulate cortex						NS	−13	−37	0	4.7
*Frontal*
Basal Forebrain			28	4	−16	5.70^*	−12	6	−18	5.01
		Lateral orbital gyrus	39	30	−18	5.14^*				NS
	Medial orbital gyrus (AS)		18	7	−21	5.33	−13	16	−18	5.07
	Medial orbital gyrus (PM)		19	21	−21	4.88				NS
	Posterior orbital gyrus (AS)		22	7	−18	5.18	−25	9	−25	4.97
	Posterior orbital gyrus (PM)		33	27	−18	5.73				NS
	Subcallosal area (AM)		10	18	−16	4.7	−12	15	−18	5.07
	Subcallosal area (PS)		6	10	−18	4.46				NS
		Orbital part of the inferior frontal gyrus	37	22	−10	4.5				NS
	Gyrus rectus (AM)		10	21	−16	4.625	−13	19	−16	4.91
	Gyrus rectus (PS)		4	22	−24	4.72				NS
*Cerebellum*
Cerebellum			34	−34	−31	4.84^*	−27	−31	−28	5.00^*

Table Legend: Specific to affect sharing: regions where affect sharing correlated significantly with gray matter volumes, adjusting for prosocial motivation, age, gender, MMSE, total intracranial volume, and magnet strength. Evident in both: regions where both affect sharing and prosocial motivation correlated with gray matter volumes, adjusting for age, gender, MMSE, total intracranial volume, and magnet strength. Specific to prosocial motivation: regions where prosocial motivation correlated significantly with gray matter volumes, adjusting for affect sharing, age, gender, MMSE, total intracranial volume, and magnet strength. All results shown in this table are corrected for family-wise error [FWE] across the whole brain at a significance level of p < 0.05. Locations of peaks are reported in MNI reference space.

Regions remaining significant after the coatrophy error check including parameterized diagnostic group in the model. NS=Not significant at pFWE < 0.05.