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. Author manuscript; available in PMC: 2019 Apr 1.
Published in final edited form as: Clin Gastroenterol Hepatol. 2017 Jul 18;16(4):504–512.e11. doi: 10.1016/j.cgh.2017.07.011

Table 3.

Threshold unit costs of the biomarker test variants allowed for equal cost-effectiveness compared to FIT.

Sensitivity CRC (%)* Specificity
88 90 92 94 96 98 100
60 −1 −1 1 3 6 8 11
70 6 9 9 12 14 17 19
80 15 17 19 21 23 25 27
90 25 27 29 32 34 35 36
100 38 40 42 44 46 48 50

CRC, colorectal cancer; FIT, fecal immunochemical test; Neg., calculated threshold cost was a negative value.

*

Although the average sensitivity for CRC is used to label the different biomarker test variants, the sensitivity for adenomas is varied accordingly (see Table 1).

The presented unit costs include costs for the test kit and the analysis of the test.