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. Author manuscript; available in PMC: 2019 Apr 1.
Published in final edited form as: Clin Gastroenterol Hepatol. 2017 Jul 18;16(4):504–512.e11. doi: 10.1016/j.cgh.2017.07.011

Table 3.

Threshold unit costs of the biomarker test variants allowed for equal cost-effectiveness compared to FIT.

Sensitivity CRC (%)* Specificity
88 90 92 94 96 98 100
60 −1 −1 1 3 6 8 11
70 6 9 9 12 14 17 19
80 15 17 19 21 23 25 27
90 25 27 29 32 34 35 36
100 38 40 42 44 46 48 50

CRC, colorectal cancer; FIT, fecal immunochemical test; Neg., calculated threshold cost was a negative value.

*

Although the average sensitivity for CRC is used to label the different biomarker test variants, the sensitivity for adenomas is varied accordingly (see Table 1).

†

The presented unit costs include costs for the test kit and the analysis of the test.