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Comparison of the O2•-/H2O2 emission rates from cardiac and liver mitochondria oxidizing pyruvate. 2-way ANOVA with a Fisher's LSD post-hoc test. n = 4, mean ± SEM. pmol min-1 mg of protein-1.
| WT | GRX2+/- | GRX2-/- | |
|---|---|---|---|
| Liver | 308.72 ± 43.75 | 203.64 ± 29.71* | 193.61 ± 18.04* |
| Cardiac | 44.96 ± 21.05## | 107.05 ± 20.02*, # | 81.20 ± 1.51*, # |
* corresponds to comparison between genotype, # corresponds to comparison between tissues within genotype. p ≤ 0.05 = * or #, p ≤ 0.01 = ##.
