Fig. 1.

Image atlas for Surface integrity of human OC tissue as detected with CEμCT (μCT or μCT with histogram stretching for enhanced contrast) or optical LM of stained tissue sections (safranin O, picrosirius, and H&E) in different samples with different OA severity: A. normal, B. mild, C. moderate, and D. severe. Similar surface morphology of AC was present in μCT compared to histological sections. Labels: z1 = zone 1, i.e., superficial AC, z2 = zone 2, i.e., middle zone, z3 = zone 3, i.e., deep AC.