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. 2018 Jan 18;8:1046. doi: 10.1038/s41598-018-19534-4

Table 2.

Association between the gamma gap and all-cause mortality according to Cox Regression Models adjusted for potential confounders.

Model 1, HR (95% CI) Model 2, HR (95% CI)
Gamma gap, continuous variable (per 1 g/dl) 1.19 (1.02, 1.67) 1.09 (1.01, 1.69)
Gamma gap, continuous variable (per 1-SD) 1.32 (1.06, 1.76) 1.22 (1.12, 1.78)
Gamma gap, dichotomized with different cut-off points
 ≥1.7 g/dl 0.96 (0.89, 1.45) 0.94 (0.86, 1.55)
 ≥1.8 g/dl 0.98 (0.95,1.02) 0.96 (0.92, 1.04)
 ≥1.9 g/dl 1.05 (0.96, 1.17) 0.99 (0.94, 1.12)
 ≥2.0 g/dl 1.12 (0.98, 1.23) 1.09 (0.91, 1.19)
 ≥2.1 g/dl 1.18 (0.87, 1.62) 1.10 (0.90, 1.67)
 ≥2.2 g/dl 1.14 (0.83, 1.87) 1.09 (0.89, 1.71)
 ≥2.3 g/dl 1.09 (0.78, 1.91) 1.07 (0.80, 1.88)
 ≥2.4 g/dl 1.19 (0.92, 1.99) 1.09 (0.94, 1.91)
 ≥2.5 g/dl 1.23 (0.95, 1.86) 1.17 (0.93, 1.77)
 ≥2.6 g/dl 1.25 (0.98, 1.71) 1.19 (0.95, 1.69)
 ≥2.7 g/dl (the median value) 1.33 (1.09, 1.88) 1.29 (0.97, 1.79)
 ≥2.8 g/dl 1.35 (1.04, 1.73) 1.31 (1.00, 1.70)
 ≥2.9 g/dl 1.32 (1.10, 1.99) 1.27 (1.12, 1.90)
 ≥3.0 g/dl 1.33 (1.05, 1.92) 1.29 (1.03, 1.78)
 ≥3.1 g/dl (the previously reported cut-off point) 1.25 (1.08, 1.57) 1.21 (1.13, 1.66)
 ≥3.2 g/dl 1.34 (1.11, 1.63) 1.26 (1.09, 1.69)
 ≥3.3 g/dl 1.37 (1.09, 1.78) 1.34 (0.97, 1.86)
 ≥3.4 g/dl 1.61 (1.20, 1.98) 1.53 (0.99, 1.87)
 ≥3.5 g/dl (the 95th percentile) 1.79 (1.13, 2.43) 1.68 (0.94, 2.12)
 ≥3.6 g/dl 1.76 (1.09,2.32) 1.54 (0.97, 2.03)
 ≥3.7 g/dl 1.81 (1.17, 3.01) 1.69 (0.91, 1.98)
 ≥3.8 g/dl 1.78 (1.03, 3.65) 1.61 (0.92, 3.47)
 ≥3.9 g/dl 1.85 (1.01, 3.32) 1.63 (0.95, 3.56)
 ≥4.0 g/dl (the traditional definition) 2.01 (0.99, 3.87) 1.98 (0.91, 3.71)
 ≥4.1 g/dl 2.09 (0.96, 3.14) 2.00 (0.89, 3.03)
 ≥4.4 g/dl (the 99th percentile) 2.12 (0.87, 3.91) 1.96 (0.86, 3.82)

Bold represents statistical significance.

Model 1: adjusted for age, gender, smoking status, alcohol drinking, and BMI. Model 2: adjusted for age, gender, smoking status, alcohol drinking, BMI, TC, TG, HDL-C, LDL-C, ALT, TB, WBC, and HGB.

ALT, alanine aminotransferase; BMI, body mass index; CI, confidential interval; HDL-C, high-density lipoprotein cholesterol; HGB, hemoglobin; HR, hazard ratio; LDL-C, low-density lipoprotein cholesterol; TB, total bilirubin; TC, total cholesterol; TG, triglyceride; WBC, white blood cell count.