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. 2018 Jan 18;8:1160. doi: 10.1038/s41598-018-19417-8

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Effect of SDF1 on the migration of c-Kit+ cells. (a) Migration of c-Kit+ cells isolated from the MI border zone treated with 100 or 200 ng/ml SDF1 or vehicle control (N = 6 for all groups) and (b) with SDF1 and/or small-molecule inhibitor of CXCR4 AMD3100 or vehicle control (N = 9 for all groups). (c) Correlation between SDF1α expression and number of c-Kit+ cells. Student’s t test was used for comparison between two groups and areas under the curve (AUC) were calculated by the summary measures method. *P < 0.05.