Table 1.
Number of genes analyzed and candidate hits identified by phenotyping mutant and wild-type mice from both sexes
| Parameter | Number of genes | Females and males (in brackets: expected number if sex equally affected) | ||||
|---|---|---|---|---|---|---|
| Females | Males | Both | Outlier <5% | Outlier >95% | Outlier <5% and >95% | |
| T0 | 1843 | 1840 | 1839 | 162 (96) | 166 (96) | 324 (192) |
| AUC 0–120 | 1846 | 1840 | 1839 | 172 (96) | 163 (96) | 334 (192) |
| Triglycerides | 1384 | 1383 | 1380 | 124 (73) | 129 (72) | 249 (145) |
| Body mass | 1649 | 1645 | 1645 | 121 (79) | 143 (86) | 264 (165) |
| Metabolic rate | 335 | 910 | 329 | 55 (48) | 53 (48) | 108 (96) |
| VO2 | 335 | 910 | 329 | 58 (48) | 52 (46) | 110 (94) |
| RER | 319 | 901 | 313 | 55 (47) | 54 (46) | 109 (93) |
| Total | 1995 | 2012 | 2016 | 575 | 587 | 974 |