Table 4.
HLA-DRB1 | RPE step 0 | RPE step 1 | ||||||
---|---|---|---|---|---|---|---|---|
Allele frequency | P-value | OR | Allele frequency | P-value | OR | |||
Controls | Cases | Controls | Cases | |||||
04:05 | 0.131 | 0.232 | 2.22E-16 | 2.00 | ||||
15:01 | 0.077 | 0.101 | 5.52E-03 | 1.35 | 0.089 | 0.132 | 4.56E-05 | 1.56 |
12:02 | 0.020 | 0.007 | 3.51E-03 | 0.34 | 0.023 | 0.009 | 0.011 | 0.39 |
16:02 | 0.008 | 0.002 | 0.025 | 0.23 | 0.010 | 0.003 | 0.043 | 0.26 |
08:02 | 0.045 | 0.048 | 0.667 | 1.07 | 0.052 | 0.062 | 0.197 | 1.22 |
04:01 | 0.009 | 0.012 | 0.396 | 1.29 | 0.010 | 0.015 | 0.205 | 1.46 |
09:01 | 0.148 | 0.112 | 1.28E-03 | 0.72 | 0.171 | 0.146 | 0.066 | 0.83 |
12:01 | 0.035 | 0.023 | 0.040 | 0.65 | 0.041 | 0.030 | 0.149 | 0.74 |
14:06 | 0.016 | 0.017 | 0.878 | 1.04 | 0.018 | 0.022 | 0.515 | 1.18 |
14:54 | 0.031 | 0.030 | 0.816 | 0.96 | 0.036 | 0.039 | 0.656 | 1.09 |
08:03 | 0.082 | 0.075 | 0.402 | 0.90 | 0.095 | 0.097 | 0.794 | 1.03 |
13:02 | 0.070 | 0.063 | 0.386 | 0.89 | 0.081 | 0.082 | 0.892 | 1.02 |
14:03 | 0.015 | 0.014 | 0.705 | 0.90 | 0.017 | 0.018 | 0.942 | 1.02 |
14:05 | 0.020 | 0.018 | 0.624 | 0.89 | 0.023 | 0.023 | 0.981 | 1.01 |
01:01 | 0.060 | 0.052 | 0.280 | 0.86 | 0.069 | 0.067 | 0.857 | 0.97 |
15:02 | 0.107 | 0.091 | 0.122 | 0.84 | 0.123 | 0.119 | 0.749 | 0.96 |
11:01 | 0.027 | 0.023 | 0.442 | 0.85 | 0.031 | 0.030 | 0.862 | 0.96 |
04:06 | 0.036 | 0.030 | 0.314 | 0.83 | 0.042 | 0.039 | 0.744 | 0.94 |
04:10 | 0.015 | 0.013 | 0.520 | 0.83 | 0.017 | 0.016 | 0.836 | 0.94 |
04:03 | 0.034 | 0.029 | 0.365 | 0.84 | 0.040 | 0.038 | 0.813 | 0.96 |
13:01 | 0.006 | 0.005 | 0.777 | 0.88 | 0.006 | 0.006 | 0.989 | 0.99 |
HLA-DQB1 | Controls | Cases | P-value | OR | Controls | Cases | P-value | OR |
04:01 | 0.131 | 0.229 | 2.22E-16 | 1.96 | ||||
06:02 | 0.072 | 0.096 | 2.74E-03 | 1.38 | 0.082 | 0.125 | 2.24E-05 | 1.59 |
03:03 | 0.160 | 0.123 | 1.49E-03 | 0.74 | 0.184 | 0.159 | 0.080 | 0.84 |
03:02 | 0.101 | 0.095 | 0.552 | 0.94 | 0.116 | 0.124 | 0.525 | 1.07 |
05:02 | 0.023 | 0.015 | 0.092 | 0.65 | 0.027 | 0.020 | 0.227 | 0.73 |
04:02 | 0.035 | 0.025 | 0.064 | 0.69 | 0.041 | 0.032 | 0.212 | 0.78 |
06:04 | 0.064 | 0.060 | 0.563 | 0.93 | 0.074 | 0.077 | 0.710 | 1.05 |
06:01 | 0.185 | 0.164 | 0.080 | 0.86 | 0.213 | 0.212 | 0.949 | 0.99 |
05:03 | 0.040 | 0.036 | 0.518 | 0.90 | 0.046 | 0.047 | 0.935 | 1.01 |
05:01 | 0.063 | 0.054 | 0.218 | 0.84 | 0.073 | 0.070 | 0.742 | 0.95 |
03:01 | 0.115 | 0.097 | 0.075 | 0.83 | 0.133 | 0.126 | 0.594 | 0.94 |
06:03 | 0.005 | 0.004 | 0.489 | 0.70 | ||||
HLA-DPB1 | Controls | Cases | P-value | OR | Controls | Cases | P-value | OR |
06:01 | 0.001 | 0.006 | 8.86E-05 | 5.24 | ||||
14:01 | 0.009 | 0.017 | 5.98E-03 | 1.97 | 0.009 | 0.017 | 5.63E-03 | 1.98 |
13:01 | 0.018 | 0.029 | 0.020 | 1.57 | 0.018 | 0.029 | 0.018 | 1.57 |
04:02 | 0.100 | 0.080 | 0.039 | 0.79 | 0.100 | 0.080 | 0.043 | 0.79 |
19:01 | 0.006 | 0.002 | 0.113 | 0.34 | 0.006 | 0.002 | 0.114 | 0.34 |
02:02 | 0.028 | 0.034 | 0.238 | 1.23 | 0.028 | 0.034 | 0.227 | 1.24 |
04:01 | 0.050 | 0.056 | 0.405 | 1.12 | 0.050 | 0.057 | 0.385 | 1.13 |
03:01 | 0.054 | 0.057 | 0.615 | 1.07 | 0.054 | 0.057 | 0.590 | 1.08 |
02:01 | 0.247 | 0.239 | 0.545 | 0.96 | 0.248 | 0.240 | 0.601 | 0.96 |
09:01 | 0.095 | 0.091 | 0.667 | 0.95 | 0.096 | 0.092 | 0.701 | 0.96 |
05:01 | 0.392 | 0.389 | 0.837 | 0.99 | 0.392 | 0.391 | 0.928 | 0.99 |