Figure 7.

Fluorescence images of cells in (A) the control group, (B) the experimental group treated with CD for 12 h, and (C) the experimental group treated with Noc for 12 h. The arrows in (B) indicate the microfilaments and the arrows in (C) indicate the microtubules. The green areas are microfilaments stained with Actin-Tracker Green, and the red areas are microtubules stained with Tubulin-Tracker Red. The scale bar represents 20 μm. (D) Comparison of statistical histograms of the Young's modulus of the cells in the experimental and control groups, measured by AFM. (E) Schematic diagram of an integrated spring from three springs in the mechanical model. (F) Comparison of the Young’s modulus and the elastic coefficient of the cells in the three groups measured by AFM and the proposed model. Significant differences were assessed at ^∗p < 0.05. To see this figure in color, go online.