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. 2018 Jan 9;114(1):201–212. doi: 10.1016/j.bpj.2017.11.010

Figure 8.

Figure 8

Axon model. Representative output of a single simulation with a prescribed stretch of λ=1.15 at a stretch rate of λ˙=0.075/ms. External force required to generate the prescribed displacement (top right), total number of cross-links and total microtubule length (bottom right), and kymographs of the microtubule positions (left), all monitored throughout the entire simulation as functions of time. Beige and brown lines highlight maximum force and maximum stretch associated with progressive axonal damage and with the complete separation of the proximal and distal ends. To see this figure in color, go online.