Table 7.
Sensitivities and Specificities of MLPA and iFISH to Detect 13q and 17p Deletions in This Present Study Compared with Previous Publications
| Study | 13q deletion | 17p deletion | |||
|---|---|---|---|---|---|
| Sensitivity | Specificity | Sensitivity | Specificity | ||
| This study | MLPA | 91.70% | 95.70% | 33.30% | 96.90% |
| iFISH | 91.70% | 95.70% | 50.00% | 94.00% | |
| Alpar et al., 2013(13) | MLPA | 88.50% | 100.00% | 100.00% | 98.70% |
| iFISH | 100.00% | 82.90% | 85.70% | 100.00% | |
| Boyle et al., 2015(25) | MLPA | 97.00% | 77.00% | 100.00% | 99.00% |
| iFISH | 100.00% | 71.00% | 100.00% | 97.00% | |
| Zang et al., 2015(31) | MLPA | 88.50% | 60.60% | 77.80% | 100.00% |
| iFISH | 63.90% | 87.00% | 100.00% | 96.20% | |