Table 1. Comparison of general characteristics and serum lipid levels between controls and patients.
Parameter | Control | CHD | IS | PCHD | PIS |
---|---|---|---|---|---|
Number | 622 | 579 | 546 | - | - |
Male/female | 446/176 | 431/148 | 394/152 | 0.286 | 0.862 |
Age, years | 61.68 ± 11.99 | 62.23 ± 10.56 | 62.87 ± 12.34 | 0.403 | 0.097 |
BMI, kg/m2 | 22.64 ± 3.20 | 23.89 ± 3.22 | 23.39 ± 3.49 | <0.001 | <0.001 |
Systolic blood pressure, mmHg | 127.39 ± 19.77 | 133.05 ± 23.29 | 147.63 ± 22.16 | <0.001 | <0.001 |
Diastolic blood pressure, mmHg | 81.28 ± 13.08 | 79.15 ± 14.20 | 83.73 ± 12.97 | 0.007 | 0.001 |
Pulse pressure, mmHg | 46.11 ± 18.27 | 53.90 ± 17.50 | 63.89 ± 17.92 | <0.001 | <0.001 |
Cigarette smoking, n (%) | 248 (39.9) | 250 (43.2) | 227 (41.6) | 0.245 | 0.554 |
Alcohol consumption, n (%) | 267 (42.9) | 134 (23.1) | 152 (27.8) | <0.001 | <0.001 |
TC, mmol/l | 4.99 ± 1.06 | 4.53 ± 1.19 | 4.52 ± 1.14 | <0.001 | <0.001 |
TG, mmol/l | 1.00 (0.71) | 1.36 (0.94) | 1.36 (0.92) | <0.001 | <0.001 |
HDL-C, mmol/l | 1.90 ± 0.50 | 1.14 ± 0.033 | 1.23 ± 0.40 | <0.001 | <0.001 |
LDL-C, mmol/l | 2.77 ± 0.78 | 2.71 ± 1.00 | 2.70 ± 0.89 | 0.272 | 0.163 |
TC/HDL-C | 2.77 ± 1.26 | 4.22 ± 1.84 | 3.96 ± 1.44 | <0.001 | <0.001 |
ApoA1, g/l | 1.41 ± 0.27 | 1.04 ± 0.52 | 1.03 ± 0.22 | <0.001 | <0.001 |
ApoB, g/l | 0.90 ± 0.21 | 0.91 ± 0.27 | 0.89 ± 0.24 | 0.713 | 0.455 |
ApoA1/ApoB | 1.65 ± 0.52 | 1.38 ± 2.48 | 1.25 ± 0.58 | 0.009 | <0.001 |
Type II diabetes mellitus, n (%) | 25 (4.0) | 95 (16.3) | 124 (22.3) | <0.001 | <0.001 |
Hypertension, n (%) | 180 (28.7) | 298 (51.0) | 272 (49.0) | <0.001 | <0.001 |
The value of TG was presented as median (interquartile range), the difference between CHD/IS patients and controls was determined by the Wilcoxon–Mann–Whitney test. Abbreviations: PCHD, CHD compared with controls; PIS, IS compared with controls.