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. 2018 Jan 19;38(1):BSR20171132. doi: 10.1042/BSR20171132

Figure 4. The effect of miR-146a-5p on GPR17 expression.

Figure 4

(A) The results predicted by online bioinformatics methods showed that GPR17 3′-UTR contained an miR-146a-5p binding site. The solid line indicated that miR-146a-5p and GPR17 could be combined, and the dotted line indicated that the binding site was mutated. (B) The luciferase activity of GPR17 3′-UTR and the expression of GPR17 in SH-SY5Y cells co-transfected with miR-146a-5p mimics and LRP. (C) The luciferase activity of GPR17 3′-UTR and the expression of GPR17 in SH-SY5Y cells co-transfected with miR-146a-5p inhibitor and LRP. *P<0.05, compared with pre-NC or NC (pre-NC was the control group of miR-146a-5p mimic. NC was the control group of miR-146a-5p inhibitor).