Table 3. Incidence rate (/100,000 person-years) of AFF identified radiologically after bisphosphonate use.
Authors | Country | Study period | Age, yr | No. of subjects | AFF | Incidence rate, % |
---|---|---|---|---|---|---|
Schilcher and Aspenberg21 | Sweden | 2005–2008 | ≥ 55 | 3,087 | 5 | 100.0a |
Tamminen et al.20 | Finland | 2007–2009 | ≥ 50 | 4,379 | 8 | 61.0 |
Meling et al.31 | Norway | 2004–2011 | ≥ 65 | 2,214 | 16 | 79.0 |
Current study | Korea | 2003–2012 | ≥ 45 | 10,338 | 13 | 85.9 (103.8a) |
AFF = atypical femoral fracture.
aIn patients with bisphosphonate for at least 3 years.