Table 3.
Characteristics and plasma levels of pre-study subjects
(Mean values and standard deviations; numbers of subjects)
| 6-g group | 3-g group | 1·5-g group | Control | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Mean | sd | Mean | sd | Mean | sd | Mean | sd | ||
| Subjects (n) | 7 | 6 | 8 | 8 | |||||
| Male | 5 | 4 | 4 | 4 | |||||
| Female | 2 | 2 | 4 | 4 | |||||
| Age (years) | 40·0 | 13·7 | 40·5 | 9·1 | 42·9 | 8·2 | 44·9 | 13·6 | |
| Height (cm) | 174·6 | 9·8 | 164·2 | 5·9 | 172·2 | 8·2 | 169·4 | 9·9 | |
| Weight (kg) | 88·8 | 18·8 | 86·8 | 14·7 | 88·1 | 14·4 | 89·0 | 13·3 | |
| Ethnicity (n) | |||||||||
| White | 3 | 2 | 3 | 2 | |||||
| Hispanic | 2 | 2 | 2 | 3 | |||||
| African-American | 1 | 1 | 1 | 1 | |||||
| Asian | 0 | 1 | 0 | 1 | |||||
| American Indian/Alaska Native | 0 | 0 | 1 | 0 | |||||
| Native Hawaian/Pacific Islander | 0 | 0 | 0 | 0 | |||||
| Other | 1 | 0 | 1 | 1 | |||||
| FPG (mg/dl)§ | Baseline | 92·2 | 8·7 | 89·3 | 4·9 | 87·7 | 4·8 | 92·3 | 6·5 |
| Week 4 | 87·5*‡ | 7·4 | 86·3‡ | 10·5 | 88·9 | 6·8 | 95·1 | 7·6 | |
| Δ FPG (mg/dl)§ | −4·7† | 6·1 | −3·0† | 3·9 | 1·1 | 6·5 | 2·9 | 5·1 | |
| Insulin (µU/ml) | Baseline | 10·4 | 9·3 | 13·2† | 0·5 | 9·1 | 4·8 | 8·9 | 4·8 |
| Week 4 | 6·8 | 2·6 | 11·7 | 11·3 | 8·8 | 4·8 | 10·0 | 6·2 | |
| Δ Insulin (µU/ml) | −3·6 | 7·7 | −1·6 | 11·5 | −0·3 | 1·7 | 1·2 | 2·0 | |
| HOMA-IR | Baseline | 2·4 | 2·1 | 2·9‡ | 0·2 | 2·0 | 1·1 | 2·0 | 1·1 |
| Week 4 | 1·4 | 0·5 | 2·5 | 2·4 | 2·0 | 1·1 | 2·4 | 1·7 | |
| Δ HOMA-IR | −0·9‡ | 1·8 | −0·4 | 2·4 | 0·0 | 0·6 | 0·4 | 0·6 | |
| TAG (mg/dl)ǁ | Baseline | 103 | 39 | 125 | 34 | 102 | 29 | 97 | 48 |
| Week 4 | 95 | 53 | 96‡ | 27 | 109 | 42 | 99 | 29 | |
| Δ TAG (mg/dl)ǁ | −9 | 50 | −29‡ | 19 | 8 | 46 | 2 | 32 | |
| BMI (kg/m2) | Baseline | 29·1 | 3·8 | 32·2 | 4·8 | 29·7 | 10·1 | 31·0 | 6·2 |
| Week 4 | 28·9*† | 1·0 | 32·0* | 4·4 | 29·9 | 12·3 | 31·0 | 6·4 | |
| Δ BMI (kg/m2) | −0·2 | 0·2 | −0·3 | 0·2 | 0·3 | 0·8 | 0·0 | 0·7 | |
FPG, fasting plasma glucose; HOMA-IR, homeostatic model assessment of insulin resistance.
* Significant difference between baseline and week 4 data (P < 0·05).
† Significant difference between test and control data (P < 0·05).
‡ Significant tendency between test and control data (P < 0·1).
§ To convert glucose from mg/dl to mmol/l, multiply by 0·0555.
ǁ To convert TAG from mg/dl to mmol/l, multiply by 0·0113.