Figure 7.
The expression of MALAT1 and miR‐125b played a key role in MM cell proliferation. NCI‐H929 and PRMI8226 cells were, respectively, transfected with Lenti‐Sh‐miR‐125b, Lenti‐Sh‐miR‐125b + Si‐NC, Lenti‐Sh‐miR‐125b + Si‐MALAT1, or Si‐MALAT1, (A) Cell viability was determined by MTT assay. (B, C) The expression of miR‐125b and MALAT1 was determined using qRT‐PCR. (D) The expression of Bcl‐2, c‐caspase3, Notch1, HES1, and β‐actin in MM cells by western blot. Data are exhibited as mean ± SD. U6, GAPDH, and β‐actin served as controls, respectively. **P < 0.01 between groups comparison.