Table 3.
Univariate and multivariate analyses of overall survival in cervical cancer patients
| Variable | Univariate analyses HR (95% CI) | P‐value | Multivariate analyses HR (95% CI) | P‐value |
|---|---|---|---|---|
| Age | ||||
| ≤46 years | 1 | 0.735 | ||
| >46 years | 1.109 (0.610–2.016) | |||
| Tumor stage | ||||
| IB | 1 | 0.011 | 1 | 0.023 |
| IIA | 2.262 (1.208–4.236) | 2.073 (1.105–3.887) | ||
| Maximum tumor size | ||||
| ≤4.0 cm | 1 | 0.022 | ||
| >4.0 cm | 2.013 (1.106–3.662) | |||
| Pathological type | ||||
| Squamous | 1 | 0.391 | ||
| Nonsquamous | 1.672 (0.517–5.408) | |||
| Adjuvant therapy | ||||
| None | 1 | 0.039 | 1 | 0.040 |
| Chemoradiotherapy | 1.620 (1.024–2.564) | 1.653 (1.024–2.668) | ||
| Radiotherapy | ||||
| Tumor grade | ||||
| G1 | 1 | 0.569 | ||
| G2 | 1.147 (0.716–1.838) | |||
| G3 | ||||
| Lymphovascular space invasion | ||||
| No | 1 | 0.555 | ||
| Yes | 1.324 (0.521–3.365) | |||
| Lymphatic metastasis | ||||
| No | 1 | 0.808 | ||
| Yes | 0.899 (0.379–2.129) | |||
| Depth of invasion | ||||
| <2/3 | 1 | 0.200 | ||
| ≥2/3 | 1.487 (0.811–2.729) | |||
| NLR | ||||
| ≤4.0 | 1 | 0.004 | ||
| >4.0 | 2.422 (1.332–4.405) | |||
| PLR | ||||
| ≤176.5 | 1 | 0.015 | ||
| >176.5 | 2.598 (1.205–5.601) | |||
| PNI | ||||
| ≤50.38 | 1 | 0.025 | ||
| >50.38 | 3.239 (1.158–9.066) | |||
| CAR | ||||
| ≤0.15 | 1 | <0.001 | 1 | <0.001 |
| >0.15 | 4.924 (2.360–10.272) | 4.729 (2.263–9.882) | ||
CAR, C‐reactive protein/albumin ratio; NLR, neutrophil to lymphocyte ratio; PLR, platelet to lymphocyte ratio; PNI, prognostic nutritional index.