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. 2018 Jan 3;175(3):469–484. doi: 10.1111/bph.14095

Figure 5.

Figure 5

TUDCA suppresses gut lipid transport genes expression. (A) The mRNA levels of ileum lipid transport‐related genes (Cd36, Fabp, Fatp4 and Ffar3) in the NCD, HFD and HFD + TUDCA groups were measured. NCD group, n = 8; HFD group, n = 9; and HFD + TUDCA, n = 6. *P < 0.05. (B) The expression levels of ileum lipid transport‐related genes were detected in Caco‐2 cells (n = 5). CON, control group treated with vehicle; PA + LPS group, Caco‐2 cells co‐stimulated with 600 μM palmitate and 10 μg·mL−1 LPS for 6 h; PA + LPS + TUDCA group, Caco‐2 cells treated with the combination of palmitate (600 mΜ), LPS (10 μg·mL−1) and TUDCA (500 mM) for 6 h. The data are presented as the means ± SEM. One‐way ANOVA followed by the Newman–Keuls post hoc test for multiple comparisons. *P < 0.05.