Figure 1.

Trabodenoson decreases IOP in young mice. (A) IOP data (mean ± SEM, n = 10) from young C57 mice obtained using rebound tonometry. Right eyes were treated topically with 3% trabodenoson, while placebo was applied topically on the contralateral left eyes. (B) These data are compared to the second cohort, which was treated with placebo in both eyes (n = 8). All mice were treated once/day for seven consecutive days. (C) The difference in IOP (delta) between the trabodenoson and placebo groups (*P < 0.05; **P < 0.01; ***P < 0.001).