Figure 5.

Trabodenoson effects on conventional outflow tissue morphology. Mouse eyes were treated with 6% trabodenoson topically in one eye and placebo in the contralateral eye once/day for seven consecutive days. At end of the study, all eyes were collected and fixed in 4% paraformaldehyde (PFA). The anterior segments were embedded in Epon and blocks were cut into 0.5 μm semithin sections and stained with 1% methylene blue. The images were captured digitally using light microscopy. Shown are representative images of sections from each quadrant of three pairs of mouse eyes that were examined. *Schlemm's canal; arrows show the trabecular meshwork (TM). CB, ciliary body.