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. 2017 Feb 17;6:71–77. doi: 10.2147/IPRP.S128816

Table 4.

Most commonly occurring drug interactions in hypertensive chronic kidney disease patients

Interacting pair Frequency Percentage
Ferrous sulfate + omeprazole 27 5.8
Calcium/vitamin D + ciprofloxacin 21 4.5
Captopril + furosemide 21 4.5
Calcium gluconate + ceftriaxone sodium 16 3.4
Calcium gluconate + ferrous sulfate 14 3.0
Ciprofloxacin + ferrous sulfate 14 3.0
Amlodipine + atenolol 13 2.8
Atenolol + prazosin 10 2.2
Amlodipine + prednisolone 9 1.9
Amlodipine + ciprofloxacin 8 1.7
Aspirin + calcium/vitamin D 8 1.7
Ciprofloxacin + metronidazole 7 1.5
Furosemide + lisinopril 7 1.5
Amlodipine + aspirin 6 1.3
Amlodipine + carbamazepine 6 1.3
Aspirin + sodium bicarbonate 6 1.3
Aspirin + insulin human regular 5 1.1
Ciprofloxacin + prednisolone 5 1.1
Amlodipine + simvastatin 4 0.9
Atorvastatin + clopidogrel 4 0.9
Carbamazepine + ciprofloxacin 4 0.9
Carbamazepine + omeprazole 4 0.9

Notes: The frequency and percentage depicted in the table is based on total 465 interactions that were observed in hypertensive chronic kidney disease patients.