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Effects of treatment with metformin and rapamycinon on tumor size in a mouse model. Mice were treated with rapamycin and metformin either in isolation or combination and the size of their tumors were measured over a period of 28 days (n=6/group). At the end of the study (28 days), statistical difference of the tumor size was observed. *P<0.05 vs. the control group; #P<0.05 vs. the metformin group; ▲P<0.05 vs. the rapamycin group.
