Table I.
Demographic characteristics.
| Characteristics | Healthy subjects (n=11) | AR only (n=25) | CARAS initially presenting with AR (n=22) | CARAS initially presenting with asthma (n=15) | P-value |
|---|---|---|---|---|---|
| Age (years) | 21.1±3.4 | 20.5±2.7 | 31.1±8.8a,b | 33.6±11.2a,b | <0.05 |
| Height (cm) | 165.1±9.0 | 165.1±7.9 | 159.6±6.2 | 159.5±8.3 | >0.05 |
| Weight (kg) | 57.0±7.8 | 53.5±7.1 | 52.2±9.6 | 58.7±10.6 | >0.05 |
| Gender (M/F) | 8/3 | 8/3 | 4/18a,b | 4/11a,b | <0.05 |
| Disease history (y) | |||||
| AR | – | 5.4±2.6 | 13.1±8.9b | 11.0±10.8b | <0.05 |
| Asthma | – | – | 3.46±4.4 | 18.1±14.1 | >0.05 |
| Allergens (n) | |||||
| Der p | – | 15 | 16 | 14 | >0.05 |
| Der f | – | 15 | 17 | 12 | >0.05 |
| Tropical mite | – | 12 | 14 | 6 | >0.05 |
| Dogs | – | 2 | 7 | 4 | >0.05 |
| Cats | – | 5 | 5 | 3 | >0.05 |
| Alternaria alternata | – | 2 | 1 | 0 | >0.05 |
| Blattella germanica | – | 3 | 9 | 7 | >0.05 |
| Mixed tree pollen | – | 0 | 0 | 0 | >0.05 |
| Mixed grass | – | 2 | 0 | 1 | >0.05 |
| FEV1%pred | 92.0±9.4 | 88.8±8.5 | 84.0±7.4a | 76.9±8.4a,b | <0.05 |
| MMEF%pred | 75.8±32.3 | 80.6±19.1 | 62.4±8.5 | 44.2±16.6b | <0.05 |
| NAR | 0.19±0.07 | 0.24±0.13 | 0.23±0.06 | 0.21±0.05 | >0.05 |
| VAS | – | 3.2±1.5 | 3.4±2.5 | 4.3±2.9 | >0.05 |
Data are expressed as the mean ± standard deviation.
a
P<0.05 vs. healthy subjects.
b
P<0.05 vs. AR only. Der p, Dermatophagoides pteronyssinus; Der f, Dermatophagoides farina; FEV1%pred, percentage of predicted forced expiratory volume in 1 sec; MMEF%pred, percentage of predicted maximal middle expiratory flow; NAR, nasal airway inspiratory resistance; VAS, visual analogue scale; AR, allergic rhinitis; CARAS, combined allergic rhinitis and asthma syndrome.